Methods for treating melanoma using small molecules
US11149028B2 · kind B2 · utility
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15Claims
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Key dates
| Filing date | Dec 15, 2017 |
| Grant date | Oct 19, 2021 |
| Priority date | — |
| Expiry date | Dec 15, 2037 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/566
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention provides methods for treating cancers, such as melanoma and/or metastatic melanoma, using compounds that interact with and/or inhibit cellular proteins lamin A/C, ATP-dependent RNA helicase DDX1 (DDX1), heterogeneous nuclear ribonuclear protein H1/H2 (hnRNP H2), and/or heterogeneous nuclear ribonuclear protein A2/B1 (hnRNP A2/B1). The invention additionally provides a method for identifying compounds active against melanoma cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.