Functionalized nanoparticles for enhanced affinity precipitation of proteins
US11149060B2 · kind B2 · utility
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17Claims
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Key dates
| Filing date | Feb 17, 2017 |
| Grant date | Oct 19, 2021 |
| Priority date | — |
| Expiry date | May 28, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y304/2207
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides a nanoparticle capable of binding specifically to a target protein in a solution and precipitating with the target protein out of the solution upon addition of the target protein to the solution. The precipitation may be reversed release the target protein from the nanoparticle, which may be reused for precipitating the target protein. Also provided are a method for purifying a target protein by affinity precipitation using the nanoparticle without chromatography and a method for preparing the nanoparticle.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.