Multispecific antibodies targeting human immunodeficiency virus and methods of using the same

US11149082B2 · kind B2 · utility

Assignees

• UNIVERSITY OF MARYLAND, COLLEGE PARK · US
• The United States of America, As Represented By · US
• International AIDS Vaccine Initiative, Inc. · US

Inventors

• Javier Guenaga · New York, US
• Yuxing Li · Boyds, US
• James STEINHARDT · Westminster, US
• John Mascola · Rockville, US

Key dates

• Filing date: Oct 17, 2017
• Grant date: Oct 19, 2021
• Expiry date: Oct 17, 2037

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2319/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present disclosure relates to multispecific antibodies targeting the human immunodeficiency virus-1 (HIV-1) envelope, methods for their production, pharmaceutical compositions containing said antibodies and uses thereof in treatment and prevention of HIV infection.