Device and method to treat esophageal disorders

US11149275B2 · kind B2 · utility

Assignee

• THE JOHNS HOPKINS UNIVERSITY · US

Inventors

• Florin M. Selaru · Baltimore, US
• Stephen J. Meltzer · Timonium, US
• George L. Coles, Jr. · Baltimore, US
• Honggang Cui · Timonium, US

Key dates

• Filing date: Oct 9, 2017
• Grant date: Oct 19, 2021
• Expiry date: Oct 9, 2037

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2320/32
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Described are devices for treating disease in subjects wherein the devices include a sponge comprising a hydrogel, extracellular vesicles (EVs), and an agent. Methods of using the devices to treat or prevent disease such as esophageal adenocarcinoma are also described.