Methods for detecting agglutination and compositions for use in practicing the same
US11149296B2 · kind B2 · utility
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7References
23Claims
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Key dates
| Filing date | Apr 15, 2016 |
| Grant date | Oct 19, 2021 |
| Priority date | — |
| Expiry date | Oct 6, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2531/113
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Methods are provided for detecting antigen binding agents in samples. Aspects of the methods include detection of the aggregation of antigen binding agents with polynucleotide-bound antigens by sensitive proximity-based association of the antigen-bound polynucleotides. Aspects of the methods also include methods for the detection of such proximity-based association through nucleic acid amplification. In addition, compositions, e.g., reagents, kits, and devices, useful in practicing various embodiments of the methods are provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.