Multi-mode imaging optical system

US11150458B2 · kind B2 · utility

Assignee

• INSTITUTE OF MEDICAL SUPPORT TECHNOLOGY, ACADEMY OF SYSTEM ENGINEERING, ACADEMY OF MILITARY SCIENCE · CN

Inventors

• Chao-Wei Li · Taipei, TW
• Meng LV · Longbeilingcun, CN
• Feng Chen · Fujian, CN
• Yaohua Du · Tianjin, CN
• Zhi Cheng · Weifang, CN
• Yanfei Yang · Tianjin, CN
• Meng-Tse Chen · Changzhi, TW

Key dates

• Filing date: Feb 7, 2020
• Grant date: Oct 19, 2021
• Expiry date: Feb 7, 2040

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2021/6478
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

The present invention discloses a multi-mode imaging optical system. The multi-mode imaging optical system includes a stage configured to hold a to-be-tested sample. An imaging unit implements in-situ imaging of the to-be-tested sample. An absorption and forward scattering illumination unit irradiates the to-be-tested sample, and forms absorption imaging or forward scattered light imaging in the imaging unit. A side scattering illumination unit performs a first oblique illumination on the to-be-tested sample, so that scattered light of microparticles in the to-be-tested sample forms side scattered light imaging in the imaging unit. A fluorescent illumination unit performs a second oblique illumination on the to-be-tested sample, and excites the microparticles in the to-be-tested sample to emit fluorescence, where the fluorescence forms fluorescence imaging in the imaging unit.