Metal-ion electrochemical biosensor and use thereof

US11154242B2 · kind B2 · utility

Assignees

• Rush University Medical Center · US
• The Board of Regents of the University of Texas System · US

Inventors

• Mathew T. Mathew · Elmhurst, US
• Shalini Prasad · Richardson, US
• Markus Wimmer · Höchst im Odenwald, DE
• Nadim James Hallab · Oak Park, US
• Joshua J. Jacobs · Wilmette, US

Key dates

• Filing date: Mar 11, 2015
• Grant date: Oct 26, 2021
• Expiry date: Apr 17, 2036

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N33/48714
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

One aspect of the invention provides a method of determining metal ion levels in the patents due to corrosion and wear processes of the metallic implant in a human or veterinary patient. One embodiment provides a cost effective and patient driven early diagnostic method which has a potential application in orthopedics and dentistry. In one embodiment, the method includes the use of an electrochemical biosensor to detect metal ions or particles in a sample taken from a patient having a metallic implant.