Method for analyzing heart rate variability, apparatus and use thereof
US11154255B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Aug 4, 2017 |
| Grant date | Oct 26, 2021 |
| Priority date | — |
| Expiry date | Mar 12, 2038 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61B5/7275
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A method for analyzing heart rate variability, and an apparatus and use thereof, the method for analyzing heart rate variability including collecting ECG data in vitro; digitizing and denoising the ECG data; forming the processed ECG data into a sinus NN interval sequence; selecting sinus NN interval data of 4 hours in an awake state; performing MSE calculation on the sinus NN interval sequence of 4 hours in an awake state; and extracting parameters representing the complexity of a heart rate by using MSE curves. The present invention may provide accurate and efficient screening for drug-refractory epilepsy patients who are suitable for vagus nerve stimulation surgery, thus avoiding unnecessary expenses, and avoiding missing the most opportune moment for treatment. At the same time, patients suitable for VNS surgery are selected by using MSE complexity feature parameters of ECG, thus improving the overall efficacy of VNS therapy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.