Burkholderia pseudomallei composition
US11154603B1 · kind B1 · utility
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Key dates
| Filing date | Jan 8, 2018 |
| Grant date | Oct 26, 2021 |
| Priority date | — |
| Expiry date | Jan 8, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/33
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A cDNA composition for reducing the virulence of Bp and reduce the cell kill and scope of the infectious disease Burkholderia pseudomallei. (Bp), which encodes fusion proteins comprised of fragments of the extracellular domains of two Bp proteins are attached to the extracellular domain (ecd) of the potent immunostimulatory protein CD40 ligand (CD40L) in order to increase the levels of neutralizing antibodies which will interfere with the function of the extracellular domains of three Bp protein peptide fragments, OMP85, VgrG5 and Hcp-1, in order to protect against a lethal challenge of Bp.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.