Hydrocodone base and methods for its purification
US11155548B2 · kind B2 · utility
0Cited by
0References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 27, 2018 |
| Grant date | Oct 26, 2021 |
| Priority date | — |
| Expiry date | Mar 27, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D489/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A method of recovering a highly pure hydrocodone base from an impure hydrocodone preparation includes contacting the impure hydrocodone preparation with a weak acid in water to form a solution and adding a strong base to the solution in an amount sufficient to precipitate the pure hydrocodone base product. A highly pure hydrocodone base comprises less than 0.0025 wt % codeinone.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.