Patent · US Active

Methods for reducing interferences

US11156610B2 · kind B2 · utility

2Cited by

2References

9Claims

0Family size

Assignee

Roche Diagnostics Operations, Inc. · US

Inventors

Barbara Upmeier · Iffeldorf, DE
Toralf Zarnt · Penzberg, DE
Johannes Polz · Ziegelberg, DE

Key dates

Filing date	Jun 13, 2017
Grant date	Oct 26, 2021
Priority date	—
Expiry date	Aug 10, 2038

Classification

Technology area (CPC G)Physics
CPC primaryG01N2800/26
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

Described is a method for determining an analyte in a sample suspected to contain the analyte, by a) contacting the sample with a first and a second capture compound for the analyte, wherein the first and second capture compounds are non-identical capture compounds, and the capture compounds compete in binding to the analyte; b) contacting the capture compounds contacted with the sample with a specifier, wherein the specifier competes in binding to the capture compounds with the analyte; c) determining the amount of complexes having the specifier and a capture compound; and d) determining the analyte in a sample based on the result of step c). Also disclosed is a method for improving the specificity of an indirect immunoassay for determining an analyte, as well as kits, devices, and uses related to the methods.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.