Pharmaceutical use of argininyl fructosy glucose
US11160820B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jun 10, 2020 |
| Grant date | Nov 2, 2021 |
| Priority date | — |
| Expiry date | Jun 10, 2040 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P1/16
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention discloses a pharmaceutical use of argininyl fructosy glucose (AFG), and belongs to the field of research and development of pharmaceutical products. The pharmaceutical use refers to application of the AFG as an active ingredient in preparation of a drug for treating or preventing an acute hepatic failure disease (AHFD). The AHFD is an oxidative stress injury caused by use of a combination of lipopolysaccharide (LPS) and D-galactosamine (D-GalN), and the drug is used for protecting liver cells from injuries, and reducing apoptosis caused by LPS/D-GalN. The purity of the AFG is 80%-99.99%. The present invention proposes the use of the AFG in prevention or treatment of the acute hepatic failure for the first time, which provides a new raw material for the preparation of the drug for the acute hepatic failure, and also provides a new method for the prevention and treatment of the acute liver failure.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.