Connective tissues, such as bone, dentin or pulp, regenerative material comprising calcium silicate

US11160905B2 · kind B2 · utility

Assignees

• SEPTODONT OU SEPTODONT SAS OU SPECIALITES SEPTODONT · FR
• UNIVERSITÉ PARIS CITÉ · FR
• INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) · FR
• Sorbonne Universite · FR
• ASSISTANCE PUBLIQUE—HÔPITAUX DE PARIS (APHP) · FR

Inventors

• Fleur Beres · Saint-Ouen, FR
• Gilles Richard · Crosne, FR
• Arnaud Dessombz · Paris, FR
• Stéphane Simon · Quimper, FR
• Juliane Isaac · Paris, FR

Key dates

• Filing date: Apr 13, 2018
• Grant date: Nov 2, 2021
• Expiry date: Apr 13, 2038

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61L2430/12
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

A regenerative material in the connective tissues (such as bone, dentin or pulp) regeneration field. More precisely, a connective tissue regenerative material, preferably a bone, dentin or pulp regenerative material, including: a porous polymer matrix having interconnected pores; and non-hydrated calcium silicate particles; wherein: the polymer matrix is anhydrous; the non-hydrated calcium silicate particles have a d50granulometry, preferably ranging from 0.05 μm to less than the average diameter size of the pores of the matrix; and the non-hydrated calcium silicate particles being coated on the inside walls of the pores of the matrix. Also, a method for preparing the connective tissue regenerative material and uses of the regenerative materials, such as in the dental field; especially, for providing regenerative materials with improved biomechanical and osteoinductive properties (i.e. good migration, adhesion and proliferation of cells; enhanced mechanical properties; and optimal and controlled biodegradability).