Compound having effects of inhibiting phosphodiesterase 4, preparation method thereof and pharmaceutical use thereof
US11161860B2 · kind B2 · utility
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7Claims
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Key dates
| Filing date | Dec 25, 2018 |
| Grant date | Nov 2, 2021 |
| Priority date | — |
| Expiry date | Dec 25, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F5/025
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The disclosure relates to the field of medicinal chemistry, in particular, to a class of small molecule compounds for inhibiting phosphodiesterase 4 (I), a preparation method thereof and a pharmaceutical composition comprising the compound. The pharmacodynamic test proves that the compound of the disclosure has the inhibitory activity of PDE-4 enzyme and the efficacy of inflammation treatment.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.