Patent · US Active

Antigen binding regions against fibronectin type III domains and methods of using the same

US11161897B2 · kind B2 · utility

0Cited by

25References

1Claims

0Family size

Assignee

JANSSEN BIOTECH, INC. · US

Inventors

Chichi Huang · Malvern, US
John Lee · Philadelphia, US
Jill Mooney · San Diego, US
Michael Naso · Union, US

Key dates

Filing date	Jul 17, 2018
Grant date	Nov 2, 2021
Priority date	—
Expiry date	Jul 17, 2038

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2319/33
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Fibronectin type III (FN3) domain antibodies, polynucleotides capable of encoding the FN3 domain antibodies or antigen-binding fragments, cells expressing FN3 domain antibodies or antigen-binding fragments, as well as associated vectors and detectably labeled FN3 domain antibodies or antigen-binding fragments may be used to engineer FN3 domain-targeting chimeric antigen receptors (CARs). Methods of making the FN3 domain antibodies, CARs, and engineered immune cells, and methods of using the engineered immune cells are applicable to treat diseases including cancer.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.