Photoprotective mixtures as imaging reagents in sequencing-by-synthesis
US11162129B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Oct 31, 2017 |
| Grant date | Nov 2, 2021 |
| Priority date | — |
| Expiry date | Jan 24, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07B2200/07
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention relates to methods, compositions, devices, systems and kits as described including, without limitation, reagents and mixtures for determining the identity of nucleic acids in nucleotide sequences using, for example, sequencing by synthesis methods. In particular, the present invention contemplates the use of photoprotective mixture of compounds as imaging reagents to improve stability and storage of fluorescent compounds, including but not limited to, nucleotides with fluorescent labels.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.