Methods for generating therapeutic delivery platforms
US11162143B2 · kind B2 · utility
Assignees
Inventor
Key dates
| Filing date | Apr 21, 2021 |
| Grant date | Nov 2, 2021 |
| Priority date | — |
| Expiry date | Apr 21, 2041 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/52
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Methods for producing engineered exosomes and other vesicle-like biological targets, including allowing a target vesicle-like structure to react and bind with immunomagnetic particles; capturing the immunomagnetic particle/vesicle complex by applying a magnetic field; further engineering the captured vesicles by surface modifying with additional active moieties or internally loading with active agents; and releasing the engineered vesicle-like structures, such as by photolytically cleaving a linkage between the particle and engineered vesicle-like structures, thereby releasing intact vesicle-like structures which can act as delivery vehicles for therapeutic treatments.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.