Vitrification of biological material

US11166453B2 · kind B2 · utility

Assignee

• THE REGENTS OF THE UNIVERSITY OF MICHIGAN · US

Inventors

• David Lai · Ann Arbor, US
• Shuichi Takayama · Ann Arbor, US
• Gary D. Smith · Ann Arbor, US
• Jun Ding · Ann Arbor, US

Key dates

• Filing date: Oct 23, 2018
• Grant date: Nov 9, 2021
• Expiry date: Jun 26, 2039

Classification

• Technology area (CPC B): Performing Operations; Transporting
• CPC primary: B01L2400/0478
• WIPO field: Basic materials chemistry
• WIPO sector: Chemistry

Abstract

Provided herein is technology relating to cryopreservation and particularly, but not exclusively, to devices, systems, and methods for cryopreservation of biological materials such as oocytes, zygotes, and embryos. In particular, provided herein are methods of using microfluidic devices to exposing biological material to a vitrification solution having a time dependent concentration of a cryoprotectant agent.