Protein formulations and methods of making same

US11167030B2 · kind B2 · utility

Assignee

• AbbVie Biotechnology Ltd. · BM

Inventors

• Wolfgang Fraunhofer · Gurnee, US
• Annika Bartl · Ludwigshafen, DE
• Hans-Juergen Krause · Havelsee, DE
• Markus Tschoepe · Heßheim, DE
• Katharina Kaleta · Ludwigshafen, DE

Key dates

• Filing date: Dec 29, 2020
• Grant date: Nov 9, 2021
• Expiry date: Dec 29, 2040

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2317/94
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention provides an aqueous formulation comprising water and a protein, and methods of making the same. The aqueous formulation of the invention may be a high protein formulation and/or may have low levels of conductivity resulting from the low levels of ionic excipients. Also included in the invention are formulations comprising water and proteins having low osmolality.