Patent · US Active

Streptavidin muteins and methods of using them

US11168116B2 · kind B2 · utility

0Cited by

4References

6Claims

0Family size

Assignee

IBA LIFESCIENCES GMBH · DE

Inventor

Thomas Schmidt · Dransfeld, DE

Key dates

Filing date	Apr 25, 2017
Grant date	Nov 9, 2021
Priority date	—
Expiry date	Apr 25, 2037

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2319/22
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The invention concerns novel streptavidin muteins and their use for determination, isolation or purification of proteins under denaturing conditions. In one embodiment such a mutein has an Cys residue at sequence position 127 of the wild-type sequence of streptavidin and comprises at least one mutation in the region of the amino acid positions 115 to 121 with reference to the amino acid sequence of wild type streptavidin.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.