Antibodies against SARS-CoV-2 and methods of using the same

US11168128B2 · kind B2 · utility

Assignee

• Vir Biotechnology, Inc. · US

Inventors

• Davide Corti · Bellinzona, CH
• Katja Fink · Singapore, SG
• Martina Beltramello · Bellinzona, CH
• Elisabetta CAMERONI · Bellinzona, CH
• Dora PINTO · Bellinzona, CH
• Gyorgy Pal Snell · South San Francisco, US
• Florian A. Lempp · San Francisco, US
• Amalio Telenti · Burgistein, CH

Key dates

• Filing date: Feb 25, 2021
• Grant date: Nov 9, 2021
• Expiry date: Feb 25, 2041

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2317/92
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The instant disclosure provides antibodies and antigen-binding fragments thereof that can bind to a SARS-CoV-2 antigen and, in certain embodiments, are capable of neutralizing a SARS-CoV-2 infection. Also provided are polynucleotides that encode an antibody or antigen-binding fragment, vectors and host cells that comprise a polynucleotide, pharmaceutical compositions, and methods of using the presently disclosed antibodies, antigen-binding fragments, polynucleotides, vectors, host cells, and compositions to treat or diagnose a SARS-CoV-2 infection.