Uridine diphosphate-dependent glycosyltransferase enzyme
US11168309B2 · kind B2 · utility
3Cited by
2References
26Claims
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Assignee
Inventors
Key dates
| Filing date | Jun 25, 2020 |
| Grant date | Nov 9, 2021 |
| Priority date | — |
| Expiry date | Jun 25, 2040 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y204/01
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
In various aspects, the present invention provides uridine diphosphate-dependent glycosyltransferase (UGT) enzymes capable of catalyzing the transfer of a monosaccharide moiety from a NDP-sugar to the 3′ carbon of a sugar moiety of a substrate, such as a terpenoid glycan, thereby functioning as a “1-3 UGT.” In other aspects, the invention provides polynucleotides encoding the 1-3 UGT, and host cells comprising the same. In still other aspects, the invention provides methods for preparing glycosylated substrates, including steviol glycosides, using the enzyme and host cells of this disclosure.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.