Mutant taq polymerase for amplification in increased salt concentration or body fluids
US11168312B2 · kind B2 · utility
1Cited by
3References
2Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 9, 2020 |
| Grant date | Nov 9, 2021 |
| Priority date | — |
| Expiry date | Mar 9, 2040 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2527/125
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention includes a mutant Taq polymerase, which can effectively amplify a target sequence under conditions of salt concentration(s) similar to body fluids, including blood, serum or plasma preserved with sodium citrate. The mutant Taq polymerase, or a biologically active fragment thereof, has one or more substitutions differing from the wild type as shown in Table I.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.