Patent · US Active

Expression of beta-glucosidases for hydrolysis of lignocellulose and associated oligomers

US11168315B2 · kind B2 · utility

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14Claims
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Key dates

Filing dateFeb 13, 2020
Grant dateNov 9, 2021
Priority date
Expiry dateFeb 13, 2040

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY02E50/10
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

The present invention provides for heterologous expression of beta-glucosidase (BGL) polypeptides encoded by Humicola grisea, Candida wickerhamii, Aspergillus aculeatus, Aspergillus oryzae, Penicillium decumbens, Chaetomium globosum, Neocallimastix frontalis, Debaryomyces hansenii, Kluyveromyces marxianus, or Phytophthora infestans in host cells, such as the yeast Saccharomyces cerevisiae. The expression in such host cells of the corresponding genes, and variants and combinations thereof, result in improved specific activity of the expressed BGL. Thus, such genes and expression systems are useful for efficient and cost-effective consolidated bioprocessing systems.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.