Placenta-derived adherent cell exosomes and uses thereof

US11173182B1 · kind B1 · utility

Assignee

• Celularity Inc. · US

Inventors

• Eric Law · Florham Park, US
• Andrew Morschauser · Florham Park, US
• Aleksander Francki · Florham Park, US
• Jennifer Paredes · Florham Park, US
• Kathy Karasiewicz-Mendez · Fryeburg, US
• Allan Reduta · Florham Park, US
• Vladimir Jankovic · New York, US
• Ivana Djuretic · San Bruno, US
• Robert J. Hariri · New York, US

Key dates

• Filing date: Jan 10, 2020
• Grant date: Nov 16, 2021
• Expiry date: Jan 10, 2040

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2502/025
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Provided herein are compositions of placenta-derived adherent cell exosomes and methods of making and using the same. In one aspect, provided herein are compositions comprising exosomes produced by and/or derived from placental cells, e.g., placenta-derived adherent cells. In certain embodiments, the exosomes provided herein are produced by placenta-derived adherent cells that have been cultured in vitro for, e.g., 1, 2, 3, 4, 5, 6 or more passages.