Iterative image reconstruction in image-guided radiation therapy

US11173324B2 · kind B2 · utility

Assignees

• VARIAN MEDICAL SYSTEMS, INC. · US
• VARIAN MEDICAL SYSTEMS INTERNATIONAL AG · CH

Inventors

• Pascal Paysan · Basel, CH
• Marcus Brehm · Erlangen, DE
• Adam Wang · Menlo Park, US
• Dieter Seghers · Zottegem, BE
• Josh Star-Lack · Palo Alto, US

Key dates

• Filing date: Apr 13, 2018
• Grant date: Nov 16, 2021
• Expiry date: Dec 25, 2039

Classification

• Technology area (CPC G): Physics
• CPC primary: G06T2211/424
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

Reconstruction of projection images of a CBCT scan is performed by generating simulated projection data, comparing the simulated projection data to the projection images of the CBCT scan, determining a residual volume based on the comparison, and using the residual volume to determine an accurate reconstructed volume. The reconstructed volume can be used to segment a tumor (and potentially one or more organs) and align the tumor to a planning volume (e.g., from a CT scan) to identify changes, such as shape of the tumor and proximity of the tumor to an organ. These changes can be used to update a radiation therapy procedure, such as by altering a radiation treatment plan and fine-tuning a patient position.