Proteins for the treatment of epithelial barrier function disorders
US11174293B2 · kind B2 · utility
1Cited by
2References
16Claims
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Assignee
Inventors
Key dates
| Filing date | Jun 1, 2018 |
| Grant date | Nov 16, 2021 |
| Priority date | — |
| Expiry date | Jul 15, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N15/85
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The disclosure relates to therapeutic proteins and pharmaceutical compositions comprising said proteins, which have utility in treating various human diseases. In particular aspects, the disclosed therapeutic proteins are useful for treating human gastrointestinal inflammatory diseases and gastrointestinal conditions associated with decreased epithelial cell barrier function or integrity. Further, the disclosed therapeutic proteins are useful for treating human inflammatory bowel disease, including inter alia, Crohn's disease and ulcerative colitis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.