Method for the production of hair follicles and de novo papillae, and use thereof for in vitro tests and in vivo implants
US11174463B2 · kind B2 · utility
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2References
15Claims
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Key dates
| Filing date | Nov 14, 2016 |
| Grant date | Nov 16, 2021 |
| Priority date | — |
| Expiry date | Oct 17, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2502/1323
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention describes a method for producing de novo papillae comprising the steps of a) providing isolated dermal papilla fibroblasts (DPF) from at least one dermal papilla (DP) from at least one hair follicle, b) providing isolated connective tissue sheath fibroblasts (CTSF) from at least one hair follicle and c) co-culturing the DPF with the CTSF under substantially non-adherent cell culture conditions to form spheroid cell aggregates.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.