Products and compositions

US11174483B2 · kind B2 · utility

Assignee

• Sapience Therapeutics, Inc. · DE

Inventors

• Sibylle Dames · Berlin, DE
• Ute Schaeper · Berlin, DE
• Judith Hauptmann · Berlin, DE
• Christian Frauendorf · Berlin, DE
• Lucas Bethge · Potsdam, DE
• Adrien Weingärtner · Berlin, DE

Key dates

• Filing date: Apr 5, 2018
• Grant date: Nov 16, 2021
• Expiry date: Jul 28, 2038

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2310/3515
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to products and compositions and their uses. In particular the invention relates to nucleic acid products that interfere with the TMPRSS6 gene expression or inhibits its expression and therapeutic uses such as for the treatment of hemochromatosis, porphyria and blood disorders such as β-thalassemias, sickle cell disease and transfusional iron overload or myelodysplastic syndrome.