Polymer microfilters, devices comprising the same, methods of manufacturing the same, and uses thereof
US11175279B2 · kind B2 · utility
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22References
9Claims
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Key dates
| Filing date | Jun 27, 2019 |
| Grant date | Nov 16, 2021 |
| Priority date | — |
| Expiry date | Jul 10, 2039 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T29/49963
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
A microfilter having a hydrophilic surface and suited for size-based capture and analysis of cells, such as circulating cancer cells, from whole blood and other human fluids is disclosed. The filter material is photo-definable, allowing the formation of precision pores by UV lithography. Exemplary embodiments provide a device that combines a microfilter with 3D nanotopography in culture scaffolds that mimic the 3D in vivo environment to better facilitate growth of captured cells.
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