Methods and compositions for preventing and treating damage to the heart

US11179439B2 · kind B2 · utility

Assignees

• MandalMed, Inc. · US
• The Regents of the University of California · US

Inventors

• Constance John · San Francisco, US
• Meenakshi GAUR · San Francisco, US
• Matthew L. Springer · San Francisco, US
• Xiaoyin Wang · San Francisco, US

Key dates

• Filing date: Jun 18, 2019
• Grant date: Nov 23, 2021
• Expiry date: Jun 18, 2039

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K9/0021
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Provided herein are methods and compositions for preventing and treating damage to the heart subsequent to myocardial infarction (MI) resulting from harmful fibrotic remodeling, thereby improving cardiac function and reducing mortality from subsequent heart failure.