Genetically modified anti-third party central memory T cells and use of same in immunotherapy
US11179448B2 · kind B2 · utility
2Cited by
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15Claims
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Key dates
| Filing date | Jul 14, 2016 |
| Grant date | Nov 23, 2021 |
| Priority date | — |
| Expiry date | Jul 14, 2036 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An isolated cell having a central memory T-lymphocyte (Tcm) phenotype, the cell being tolerance-inducing cell and capable of homing to the lymph nodes following transplantation, the cell being transduced to express a cell surface receptor comprising a T cell receptor signaling module is disclosed. Methods of generating same and using same are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.