Oxopiperazine helix mimetics as inhibitors of the p53-MDM2 interaction
US11180481B2 · kind B2 · utility
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10Claims
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Key dates
| Filing date | Apr 15, 2015 |
| Grant date | Nov 23, 2021 |
| Priority date | — |
| Expiry date | Apr 15, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D403/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to oligooxopiperazines for modulating the p53-Mdm2 interaction. Exemplary oligooxopiperazines include those of Formula IA, Formula IB, and Formula IC below (wherein the various substituents are as defined herein). Methods of using the oligooxopiperazines are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.