[1,2,4]Triazolo[4,3-A]pyrazin-6(5H)-one derivatives
US11180503B2 · kind B2 · utility
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4References
12Claims
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Key dates
| Filing date | Jul 26, 2018 |
| Grant date | Nov 23, 2021 |
| Priority date | — |
| Expiry date | Sep 6, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D471/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention provides a compound of Formula (I), wherein X is H or C1-C3 alkyl optionally substituted with hydroxyl; Y is H, hydroxy, or methyl; R is ethyl, n-propyl, cyclopropyl, or Formula (II); and A is methyl, cyclopropyl or trifluoromethyl; or a pharmaceutically acceptable salt thereof; with the proviso that when X and Y are both H and R is n-propyl, then A is other than methyl; for use as a human PDE1 inhibitor.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.