Combinatorial gene construct and non-viral delivery for anti-obesity
US11180538B2 · kind B2 · utility
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5References
16Claims
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Key dates
| Filing date | Mar 25, 2016 |
| Grant date | Nov 23, 2021 |
| Priority date | — |
| Expiry date | Mar 27, 2038 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K48/0075
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides a plasmid comprising two or more anti-obesity genes. Also provided by the invention are compositions and host cells comprising the plasmid and methods of increasing the metabolic activity in a mammal. The invention provides a plasmid comprising two or more of (a) a nucleic acid sequence encoding islet amyloid polypeptide (IAPP), (b) a nucleic acid sequence encoding leptin (LEP), and (c) a nucleic acid sequence encoding fibronectin type III domain containing 5 (FNDC5).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.