Patent · US Active

In-vitro full-skin model containing three-dimensional cell culture models of the sweat gland

US11180728B2 · kind B2 · utility

0Cited by

0References

20Claims

0Family size

Assignee

Henkel AG & Co. KGaA · DE

Inventors

Patricia Klaka · Leverkusen, DE
Sabine Gruedl · Erkelenz, DE
Melanie Giesen · Geldern, DE
Thomas Welss · Dressendorf, DE
Bernhard Banowski · Goldkronach, DE
Lars Vierkotten · Overath, DE

Key dates

Filing date	Mar 20, 2017
Grant date	Nov 23, 2021
Priority date	—
Expiry date	Jun 11, 2038

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2533/54
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

The present disclosure concerns an in-vitro full skin model which comprises a dermal equivalent and epidermal equivalent as well as from about 1 to about 100 three-dimensional sweat gland equivalents with respectively from about 500 to about 500000 sweat gland cells as well as a diameter of respectively from about 100 to about 6000 μm on a supporting layer. Furthermore, the present disclosure concerns the production of the full skin model as well as the use of this model as an in-vitro model, in screening methods as well as for in-vitro evaluation of the influence of cosmetic substances on the inhibition of sweat secretion as well as body odor.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.