Patent · US Active

Method for producing chiral amines

US11180783B2 · kind B2 · utility

0Cited by
2References
20Claims
0Family size

Assignee

Inventors

Key dates

Filing dateAug 31, 2018
Grant dateNov 23, 2021
Priority date
Expiry dateAug 31, 2038

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N9/1096
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

A method for producing a chiral amine may include performing a transamination reaction of a prochiral amino acceptor and an amino donor in a first solution in the presence of a transaminase, thereby forming a chiral amine and a co-product in the first solution. The amino donor is a high molecular weight (HMW) amino donor. In some examples, the molecular weight of the HMW amino donor is at least 150 g/mol. In some examples, the amino donor is affixed on a support, the total molecular weight of the amino donor and the support being at least 150 g/mol.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.