Skin external preparation composition for moisturizing skin containing 1,2,3,4,6-penta-O-galloyl-β-D-glucose
US11185488B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jul 31, 2018 |
| Grant date | Nov 30, 2021 |
| Priority date | — |
| Expiry date | Jul 31, 2038 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61Q19/007
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A skin external composition containing 1,2,3,4,6-penta-O-galloyl-β-D-glucose (hereinafter referred to as “PGG”) and its use to improve moisture balance of skin are disclosed. The skin external composition, due to containing PGG, stimulates the formation of filaggrin in keratinocytes, increases loricrin and involucrin expression, thereby stimulating the formation of a normal keratin layer, and as a result, can strengthen the skin barrier function to provide an excellent skin moisturization improving effect. Thus, the composition is effective in improving moisture balance of skin. A method for moisturizing the skin using the composition is also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.