Stable liquid composition comprising botulinum toxin
US11185503B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Oct 17, 2017 |
| Grant date | Nov 30, 2021 |
| Priority date | — |
| Expiry date | Oct 17, 2037 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A stable liquid composition comprising a botulinum toxin as an active ingredient is described, which is ready-to-use without the need for a reconstitution process, and thus, it is possible to improve user's convenience, and reduce a deviation of botulinum toxin activity due to dilution errors in the reconstitution process. Further, the liquid composition efficiently prevents the botulinum toxin from aggregating even at a low botulinum toxin concentration to thereby have extremely excellent storage stability, and efficiently prevents adsorption of the botulinum toxin to a container, thereby constantly maintaining an activity of the botulinum toxin for each batch or for each liquid vial.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.