Patent · US Active

Antiproliferative compounds and methods of use thereof

US11185543B2 · kind B2 · utility

4Cited by
12References
20Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 27, 2020
Grant dateNov 30, 2021
Priority date
Expiry dateApr 27, 2040

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K2300/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Provided herein is 4-(4-(4-(((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)oxy)methyl)benzyl)piperazin-1-yl)-3-fluorobenzonitrile, or an enantiomer, a mixture of enantiomers, a tautomer, or a pharmaceutically acceptable salt thereof, and methods for treating, preventing or managing multiple myeloma using such compounds. Also provided are pharmaceutical compositions comprising the compounds, and methods of use of the compositions.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.