Patent · US Active

Alkylating agent for alkylating target with driver oncogene mutation

US11185593B2 · kind B2 · utility

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0References
17Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJul 1, 2020
Grant dateNov 30, 2021
Priority date
Expiry dateJul 1, 2040

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC08G73/0616
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention provides a novel alkylating agent specifically binding to the genetic mutation site of a driver oncogene. There are provided are a complex formed by binding an alkylating agent to a pyrrole imidazole polyamide specifically binding to the genetic mutation site of a driver oncogene, a driver oncogene mutation-specific alkylating agent comprising the aforementioned complex, and a pharmaceutical composition comprising the aforementioned complex.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.