Method for filling pharmaceutical containers

US11186390B2 · kind B2 · utility

Assignee

• VANRX PHARMASYSTEMS INC. · CA

Inventors

• Nick Broadbent · Vancouver, CA
• Jeroen IMMERZEEL · Squamish, CA
• Christopher Procyshyn · Surrey, CA
• Ross M. Gold · North Vancouver, CA
• Steve Sang Joon Park · Syosset, US

Key dates

• Filing date: Jan 2, 2019
• Grant date: Nov 30, 2021
• Expiry date: Jun 20, 2039

Classification

• Technology area (CPC B): Performing Operations; Transporting
• CPC primary: B65D51/002
• WIPO field: Handling
• WIPO sector: Mechanical engineering

Abstract

In one general aspect, a method for filling multiple containers with a pharmaceutical product is disclosed, which comprises decontaminating sealed nested materials in a transfer chamber, removing from the sealed nested materials one or both of a container nest holding the multiple containers and a closure nest holding multiple closures, transferring from the transfer chamber to a controlled environment enclosure the removed nest, aseptically filling the containers with the pharmaceutical product, and closing the containers with the multiple closures. The nests are configured to allow multiple closures and containers to be simultaneously aligned concentrically, and closed simultaneously. Spring-loaded retaining structures on the closure nest allow it to releasably retain multiple closures above the corresponding multiple containers. In some embodiments the spring-loaded features are monolithically integrated with the closure nest. The product may be lyophilized in partially sealed containers while the sealing closures are releasably retained by the closure nest.