Patent · US Active

Difluoromethyl-aminopyridines and difluoromethyl-aminopyrimidines

US11186591B2 · kind B2 · utility

2Cited by
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14Claims
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Key dates

Filing dateMar 13, 2020
Grant dateNov 30, 2021
Priority date
Expiry dateMar 13, 2040

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D519/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The invention relates to novel phosphoinositide 3-kinase (PI3K), mammalian target of rapamycin (mTOR) and PI3K-related kinase (PIKKs) inhibitor compounds of formula (I), wherein X1, X2 and X3 are N or CH, with the proviso that at least two of X1, X2 and X3 are N; Y is N or CH, These compounds are useful, either alone or in combination with further therapeutic agents, for treating disorders mediated by lipid kinases.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.