Method for the identification of immunotherapy-drug combinations using a network approach
US11186640B2 · kind B2 · utility
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24Claims
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Key dates
| Filing date | Jul 31, 2015 |
| Grant date | Nov 30, 2021 |
| Priority date | — |
| Expiry date | Mar 22, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/76
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to systems and methods for evaluating the differentiality of a set of discrete random variables between two or more conditions, such as a malignant condition responding to treatment regime and one that is not. It also provides for the identification and selection of drugs that act in coordinated manner to phenocopy a genetic network of a malignant condition that responds to at least an immune checkpoint blockade agent.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.