Compounds and methods of treating retinal degeneration
US11191752B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Apr 30, 2018 |
| Grant date | Dec 7, 2021 |
| Priority date | — |
| Expiry date | May 10, 2038 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P29/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This application relates to compounds and methods of treating retinal degeneration associated with inherited rhodopsin mutations in the ocular tissue of a subject. The retinal degeneration, can include, for example, macular degeneration, a including age-related macular degeneration, Stargardt disease, and retinitis pigmentosa. The retinitis pigmentosa can include autosomal dominate retinitis pigmentosa associated with a P23H RHO mutation. A method of treating retinal degeneration in a subject includes administering to the subject a therapeutically effective amount of a compound of formula (I), wherein the compound of formula (I) acts as a chaperone of rhodopsin.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.