Patent · US Active

Scalable process for oncolytic rat parvovirus H-1 production and purification based on isoelectric point-based elimination of empty particles

US11193112B2 · kind B2 · utility

1Cited by

0References

7Claims

0Family size

Assignee

Deutsches Krebsforschungszentrum · DE

Inventors

Barbara Leuchs · Heidelberg, DE
Jean Rommelaere · Heidelberg, DE
Veronika FREHTMAN · Heidelberg, DE
Markus Riese · Worbis, DE

Key dates

Filing date	May 1, 2019
Grant date	Dec 7, 2021
Priority date	—
Expiry date	May 1, 2039

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2750/14351
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The present invention provides a reproducible, effective and scalable process for the purification of (infectious) parvovirus H-1 particles. The purification process allows the separation of empty particles from particles containing a full genome and is compatible with large-scale H-1PV production for clinical applications.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.