Trans-tympanic membrane delivery platform and uses thereof
US11197820B2 · kind B2 · utility
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3References
8Claims
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Key dates
| Filing date | Apr 27, 2020 |
| Grant date | Dec 14, 2021 |
| Priority date | — |
| Expiry date | Apr 27, 2040 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S977/907
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided herein are methods and composition for trans-tympanic membrane delivery of therapeutic agents such as antimicrobial agents, anti-inflammatory agents, and anti-biofilm agents to the middle ear for rapid, localized treatment and prevention of diseases and conditions associated with a middle ear infection. In particular, provided herein are cationic, anionic, and polymer-based nanoparticles that provide a platform for delivery of therapeutic cargo, as well as cationic, anionic, and polymer-based nanoparticles compositions for rapid, localized delivery of therapeutic agents to the middle ear.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.