Methods, systems and kits for in-pen assays

US11203018B2 · kind B2 · utility

Assignee

• Berkeley Lights, Inc. · US

Inventors

• Troy A. Lionberger · Berkeley, US
• Matthew E. Fowler · Emeryville, US
• Phillip J. M. Elms · Emeryville, US
• Kevin D. Loutherback · Emeryville, US
• Randall D. Lowe, Jr. · Emeryville, US
• Jian Gong · Danville, US
• J. Tanner Nevill · El Cerrito, US
• Gang F. Wang · Mountain View, US
• Gregory G. Lavieu · Vitry-sur-Seine, FR
• John A. Tenney · Piedmont, US
• Aathavan Karunakaran · Berkeley, US
• Anupam Singhal · Emeryville, US
• I-Jong Lin · El Granada, US

Key dates

• Filing date: Oct 15, 2018
• Grant date: Dec 21, 2021
• Expiry date: Oct 15, 2038

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2201/0675
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Methods, systems and kits are described herein for detecting the results of an assay. In particular, the methods, systems and devices of the present disclosure rely on a difference between the diffusion rates of a reporter molecule and an analyte of interest in order to quantify an amount of analyte in a microfluidic device. The analyte may be a secreted product of a biological micro-object.