Patent · US Active

Factor VII polypeptides that are modified and uses thereof

US11203749B2 · kind B2 · utility

1Cited by
45References
6Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 2, 2018
Grant dateDec 21, 2021
Priority date—
Expiry dateNov 2, 2038

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K2319/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Nucleic acids encoding modified factor VII polypeptides, vectors and cells containing the nucleic acids, uses of the nucleic acids, methods of making the encoded polypeptides, and methods of treatment are provided. The encoded modified FVII polypeptides include Factor VIIa and other forms of Factor VII. Among the encoded modified FVII polypeptides provided are those that have altered activities, typically altered procoagulant activity, including increased procoagulant activities.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.