Systems and methods for treatments of an eye with a photosensitizer
US11207410B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jul 21, 2016 |
| Grant date | Dec 28, 2021 |
| Priority date | — |
| Expiry date | Aug 14, 2036 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61N2005/0661
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A formulation for an eye treatment includes a photosensitizer and a permeability enhancing composition. The permeability enhancing composition includes one or more permeability enhancers. The permeability enhancing composition has a hydrophilic and lipophilic balance increases a permeability of an area of the eye for the photosensitizer. The hydrophilic and lipophilic balance can be characterized by a Hydrophile-Lipophile Balance (HLB) number. For example, the area of the eye may include a corneal epithelium, the photosensitizer may include riboflavin, and the permeability enhancing composition may have a corresponding HLB number between approximately 12.6 and approximately 14.6.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.